All the information below is strictly for research purposes only. Under no circumstance should this chemical be used for human consumption.
The regulation of Actin, a cell building protein, is also a major player in the potential effectiveness of TB-500. Actin, which is imperative to cell movement and structure, makes up around 10% of the total of all proteins in each cell, despite the fact that each cell contains thousands of proteins. This alone is indicative of the major role it plays in the design of each cell on a genetic level.
The peptide is part of a family of 16 molecules. These molecules work to localize and conserve the sequence in much of the body tissue and circulating cells. TB-500 not only binds to actin, but it is also able to sequester actin in eukaryotic cells and block polymerization.
It is believed to be an up-regulated gene. That is, it speeds the formation of blood vessels by 4 to 6 times the normal speed, and also encourages new blood cells from the vessels already there. The naturally occurring version of this peptide is found in fluid under wounds, and it has been show that when this man-made version is injected under the skin, muscle rebuilding and healing of the wound are encouraged. Studies have also shown that recovery time is shortened.
In addition, TB-500 interacts with actin at the cytoskeleton level of a cell, encouraging cell migration. The small amino acid long-actin binding domain has shown that it can speed wound healing and the production of blood cells. This along with the acceleration of keratinocytes and endothelial cell migration seems to produce a more extracellular matrix-degrading enzyme.
Recent research and current studies have shown that TB-500 has great potential as a strong wound repair factor, and that is also has anti-inflammatory factors. It can travel long distances through tissues due to its lower molecular weight, and it does not bind with the extra cellular matrix. This is unique from other repair factors such as growth factors, as it its ability to promote the migration of keratinocyte and endothelial migration.
Chemical and other safety information:
H-statements (GHS/CLP): P-statements (GHS/CLP): H302: Harmful if swallowed. P102: Keep out of reach of children. H315: Causes skin irritation P232: Protect from moisture. H319: Causes serious eye irritation. P235: Keep cool. H332: Harmful if inhaled. P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P264: Wash hands thoroughly after handling. P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P302+P352: IF ON SKIN: Wash with plenty of soap and water. P301+P330+P331: IF SWALLOWED: rinse mouth. Do NOT induce vomiting. P332+313: If skin irritation occurs: Get medical advice/attention. P411+235: Store at temperatures not exceeding 8°C/46°F. Keep cool
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